Monkeypox has an incubation period which lasts on average 7-14 days. The disease has a set of initial symptoms like fever, malaise, headache, weakness and more, which lead into full development of symptoms. A rash appears after the initial period, with lesions typically begin to develop simultaneously and evolving together on any given part of the body, including the mouth.
A person is contagious from the onset of the rash through the scab stage.
The severity of illness can depend upon the initial health of the individual, the route of exposure and the strain of the infecting virus.
A feature that distinguishes infection with monkeypox from that of smallpox is the development of swollen lymph nodes. Swelling of the lymph nodes may occur in many different locations on the body or can be localized to several areas like the neck and armpit.